Age Reversal Breakthrough: Harvard/MIT Discovery Could Enable Whole-Body Rejuvenation::In a pioneering study, researchers from Harvard Medical School, University of Maine, and MIT have introduced a chemical method for reversing cellular aging. This revolutionary approach offers a potential alternative to gene therapy for age reversal. The findings could transform treatments for age-re

      • TWeaK@lemm.ee
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        1 year ago

        Peter Thiel and probably Donald Trump have supposedly been injecting themselves with children’s blood, or at least a derivative from their blood.

    • Piecemakers@lemmy.world
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      Jokes aside, are we just cribbing from sci-fi cart blânche these days?! I mean, sure “Art imitates Life imitates Art”, but still. When the only dead are the poors (>99% of humanity itself), the entire species will certainly collapse. (Where’s the “bridge of nose pinch + sigh” emoji when you need it?) 🤷🏼‍♂️

          • Tesco@lemmy.world
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            1 year ago

            At first it isn’t, but as you go more and more grey it becomes a lot harder to manage on your own, especially if you started with dark hair. It’s depressing to be young and constantly fighting a losing battle against the grey. I was like 16 when it started, by my very early 30s the whole of the top of my hair was completely grey.

  • drapermache@lemmy.world
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    1 year ago

    Couldn’t you wait until Mitch Mconnell died until you released this? I’d rather not him be in the senate forever.

  • evranch@lemmy.ca
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    Full text of actual paper: https://www.aging-us.com/full/204896

    Tldr; seems like decent science and the compounds used are fairly ordinary ones for the most part. Note however this is all in vitro so far and it might be a challenge to deliver the same chemicals in the same concentrations to all the senescent cells of the body.

    Prepare to see these ingredients added in insignificant amounts to expensive skin creams before the year is out, whether they can penetrate the epidermis or not

    • belshamharoth@lemmy.world
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      1 year ago

      The full journal article says “in vivo” not “in vitro”. They have already successfully regenerated mice which are organisms biologically similar to humans.


      Edit

      I was wrong about this. The journal article does only talk about results obtained “in vitro” but mentions other studies that have successfully reversed cellular ageing “in vivo”.

      The ability of the Yamanaka factors to erase cellular identity raised a key question: is it possible to reverse cellular aging in vivo without causing uncontrolled cell growth and tumorigenesis? Initially, it didn’t seem so, as mice died within two days of expressing OSKM. But work by the Belmonte lab, our lab, and others have confirmed that it is possible to safely improve the function of tissues in vivo by pulsing OSKM expression [22, 23] or by continuously expressing only OSK, leaving out the oncogene c-MYC

      So in this study the results were only in vitro but other studies have successfully reversed cellular ageing in vivo.

    • foggy@lemmy.world
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      Worry? I’m excited for it man.

      They don’t realize they’re messing with a monkeys paw.

      The first gen lifers are gonna live to regret their discovery.

  • CaffeinatedOne@lemmy.world
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    Even if for the rich, this would be good news. The rich and powerful will stop ignoring things like distant climate related deadlines, if they think they’ll be alive to feel their effects.

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      If this take is anything like whales with stock they’ll just jump ship onto the next country/planet to start over it’s a never ending cycle

      A lot of the rich/ultra wealthy are selfish and don’t give a fuck unless it directly affects them so I don’t foresee any accountability if the planet Implodes instead they’ll just fling their money at the next thing that buys them a ticket out of here

  • zensoup@lemmy.world
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    Ahh, immortal super-rich people whose views get more and more conservative as they age forever… What an exciting future to look forward to!

    • CodeInvasion@sh.itjust.works
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      The only upside I can think of is they’d actually start caring about the planet instead of thinking they’ll be dead in 100 years anyway.

      • gdrhnvfhj@lemmynsfw.com
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        They try to get so rich no matter what, so they can evade all consequences. (That’s not possible, but they want to believe it)

    • TheCraiggers@lemmy.world
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      I see one potential good thing though: maybe people would be less interested in killing the only planet that supports human life if they knew they were going to be on it forever.

  • RandomBit@lemmy.sdf.org
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    The sci-fi type implications of this would be astounding. We would see a rapidly increasing global population with high natural resource use. On a philosophical level, is living forever a blessing or a curse?

        • AB7ORH7D@lemmy.world
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          With term limits of course. Idk there could be a possibility that they’d take the planet seriously though as they’d be around to see the consequences of environmental policy

          • InverseParallax@lemmy.world
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            Idk there could be a possibility that they’d take the planet seriously though as they’d be around to see the consequences of environmental policy

            I’m more of the school of thought that “THERE CAN BE ONLY ONE!!!” and in the grim dark future of immortal oligarchs, there is only war.

    • Stovetop@lemmy.world
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      I doubt that will be the reality of any such breakthroughs, at least not for a long time. But I think the solution in such a scenario would have to be sterilization of everyone on earth by default. Sterilization which could be temporarily reversed to allow someone to have a child via a controlled application process just to meet the rate of replacement.

      • TWeaK@lemm.ee
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        1 year ago

        Sometimes paywalls only hit you after you’ve visited a handful of articles.

  • Shaggy0291@lemmygrad.ml
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    Biochemist here, It’s almost certainly an overhyped study. The operative term being used here is “potentially” full body rejuvenation is possible. It doesn’t address issues such as administration of the therapy in tissues with virtually no turnover rate, including cardiac tissue, skeletal muscle, and nervous tissue. You cannot renew something that the body doesn’t naturally replace via the cell cycle.

  • nitefox@lemmy.world
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    The comments be like: I didn’t read the article, here my pissed off reaction calling for 1984

    • cottard@lemmy.world
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      1 year ago

      Thanks for reminding me to prioritize the capacity for dignified exit from the game.

  • MrBungle@lemmy.ca
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    1 year ago

    Ugh. I barely want to live my whole life on this planet with the ways it is going… let alone reverse back into my 20s with no actual “new game+”