Gödel, Escher, Bach: an Eternal Golden Braid by Douglas Hofstadter

I’m surprised no one has mentioned The Culture series by Iain M. banks. Much like Dune there is a ton of world building that occurs in the novels but it’s not the focus of any one novel. You can read them independently and still enjoy them. The concepts he tackles in the novels were way ahead of their time and his prose and s second to none. The novel Consider Phlebas is typically where most people start, but I started The Player of Games.